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Blueprint Bio

Active

Looking for a team member

Chemical processes + compounds, biotech and pharmaceuticals

Health and wellbeing

Medical devices and diagnostics
We aim to develop a next-generation enzymatic DNA synthesis technology that enables rapid, low-cost, and sustainable production of complex nucleic acids. This platform will empower synthetic biology, drug discovery, and vaccine development. We have developed a novel engineered enzyme capable of template-independent DNA synthesis that can incorporate reversibly blocked nucleotides. Initial validation experiments confirmed its activity. We are optimising reaction conditions to further improve synthesis efficiency. Our goal is to demonstrate the enzymatic synthesis of a small gene using blocked nucleotides and further engineer the enzyme to enhance performance. The project started at the end of Paola’s PhD on polymerase engineering for xenobiotic nucleic acid (XNA) synthesis, when she explored the idea of engineering a novel polymerase for de novo DNA, RNA, and XNA synthesis. Early experiments showed promising results. During her postdoctoral research at ETH Zurich, she met Jelmi and Jan-Phillip, and together they decided to further develop the project and explore its potential....
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BrickMachine

Active

Looking for a team member

Data-driven & Machine Learning

Environmental Sustainability

Hardware Engineering & Robotics

Software Engineering
Unsere Vision ist es, den Klemmbausteinmarkt nachhaltiger und effizienter zu gestalten. Weltweit existieren über 1 Billion LEGO-Steine, von denen viele ungenutzt bleiben, da manuelles Sortieren zeit- und kostenintensiv ist. Nach über drei Jahren Entwicklungszeit haben wir einen vollfunktionsfähigen Prototyp einer automatisierten LEGO-Sortiermaschine entwickelt und erfolgreich getestet. Wir bieten nun unseren Service sowohl im B2C-Bereich für private LEGO-Sammlungen als auch im B2B-Umfeld für Händler, Wiederverkäufer und Organisationen an. Das Projekt begann während unseres letzten Schuljahres, als wir LEGO-Steine von Hand sortierten und weiterverkauften, um unser Taschengeld aufzubessern. Dadurch mussten wir schnell feststellen wie nervig und zeitaufwändig die Sortierung von gebrauchten Steinen wirklich ist....
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BuildMeUp

Active

Looking for a team member

Education

Hardware Engineering & Robotics

Social Impact
Empowering students to pursue a career in STEM (MINT). I want to inspire gymnasium-level students to discover robotics as a tool for solving real-world problems. By building and experimenting, they develop a mindset that blends human adaptiveness with machine capabilities. They should gain confidence in their skills and notice opportunities around them where technology can make a difference. Just as importantly, I want to demystify engineering by showing that progress comes from simplifying intelligently. As a student, I believed real engineering would be dull and “crazy complicated” because high-school simplifications wouldn’t apply. Now the goal is to show that choosing the right simplifications is powerful - and often the most exciting part of engineering: knowing what matters and what can be left out of the model. All models are wrong, but some are useful....
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EduForma

Active

Looking for a team member

Community empowerment

Data-driven & Machine Learning

Education
The Mission:EduForma is an AI co-pilot that automates the entire planning workflow for Swiss teachers—from high-level yearly roadmaps to granular lesson plans. By solving the complex mapping of Lehrplan 21, we eliminate administrative burnout and return the focus to high-quality teaching.The Tech & StatusI have developed a functional MVP (FastAPI/React) integrated with LLMs, hosted on a secure Azure (CH) infrastructure. The core engine is built to handle localized curriculum data and is currently undergoing internal testing.The GoalMy immediate priority is to gather direct user feedback from Swiss educators to refine the UX and functionality. The ultimate vision is to transform the Swiss education system by making compliant, high-standard lesson preparation an effortless, 5-minute task....
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Eureka! Microscope

Active

Looking for a team member

Consumer Apps

Consumer goods

Education

Hardware Engineering & Robotics
Portable microscope for fun and science education. Our vision is to democratize the fun of nature discovery and to connect people with the environment in a unique way. We encourage people to explore the hidden wonder of nature and to learn the scientific knowledge behind. We have developed a prototype with a resolution of 1.6µm and multiple visual effects, at a price of $200. We secured pilot customers with CHF 13k in commitment, got CHF 10k from Venture Kick, and built a waitlist of 100+ early adopters. Our main goal is to turn microscopes into a new category of consumer electronics by offering not just hardware, but also an app for discovery and curiosity. Siyi, the CEO of Eureka! Microscope, found microscopy very fascinating. After realizing most people in the world can't enjoy the experience because a good product hasn't existed yet, she invited her friend Yu (CTO), who is passionate about cool technology, to join the venture....
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Orbiit

Active

Hiring

Looking for a team member

Community empowerment

Consumer Apps

Professional services and consulting
Orbiit is a compatibility-based matchmaking platform for both friends and partners. Users create a profile and complete a survey focused on values, communication style, needs, and goals. Instead of offering endless options, we provide curated matches designed for genuine alignment. When both people agree, we coordinate the logistics to help them meet in real life. Orbiit was created in response to growing swipe fatigue and superficial digital interactions. We noticed that many platforms optimize for engagement rather than real compatibility. Orbiit was built to shift the focus back to quality, clarity, and meaningful in-person connection. We’ve launched our first in-person matchmaking events and attracted over 100+ early users through word-of-mouth and campus outreach. Our main goal is to develop a research-backed dating app that offers compatibility-based matching and real-world meetups, creating a more intentional and emotionally intelligent way to date. The project started after a breakup, when one of the co-founders began dating again and realised the dating world felt disconnected and surface-level. She shared her experience with her best friend and now co-founder, and together they decided to create a platform that could offer something better. Fly into Orbiit with us....
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Recycling 3D Printer Plastics

Active

DIY Build

Looking for a team member

Education

Environmental Sustainability

Open source
After finding out that SPH doesn't recycle its waste plastic from the 3D printers, I wanted to do something about that. Recycling these plastics is possible, and with enough care taken to sort them, they can be reused for 3D printing with results comparable to original filament. The extrusion is then carried out with an Artme MK3. Most of the input material is failed 3D prints, design iterations, and support material. That needs to be sorted for a high quality result, removing impurities and other types of plastics. One difficulty for reaching a good quality result is purity: PLA and PETG need to be reliably separated. After shredding into granules, the material is extruded into 1.75+/-0.03mm filament. This is comparable to Prusa's commercial PRUSAMENT at 1.75+/-0.02mm. ...
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