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Blueprint Bio

Active

Looking for a team member

Chemical processes + compounds, biotech and pharmaceuticals

Health and wellbeing

Medical devices and diagnostics
We aim to develop a next-generation enzymatic DNA synthesis technology that enables rapid, low-cost, and sustainable production of complex nucleic acids. This platform will empower synthetic biology, drug discovery, and vaccine development. We have developed a novel engineered enzyme capable of template-independent DNA synthesis that can incorporate reversibly blocked nucleotides. Initial validation experiments confirmed its activity. We are optimising reaction conditions to further improve synthesis efficiency. Our goal is to demonstrate the enzymatic synthesis of a small gene using blocked nucleotides and further engineer the enzyme to enhance performance. The project started at the end of Paola’s PhD on polymerase engineering for xenobiotic nucleic acid (XNA) synthesis, when she explored the idea of engineering a novel polymerase for de novo DNA, RNA, and XNA synthesis. Early experiments showed promising results. During her postdoctoral research at ETH Zurich, she met Jelmi and Jan-Phillip, and together they decided to further develop the project and explore its potential....
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House Of Charts

Alumni

Data-driven & Machine Learning

Health and wellbeing

Medical devices and diagnostics

Software Engineering
House of Charts revolutionizes hospital workflows by using advanced AI to automate clinical documentation, allowing medical staff to focus on patient care. Their privacy-preserving technology generates discharge reports, medical coding, and other essential documents, seamlessly integrating with existing systems to enhance efficiency across all specialties. ...
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Menstruation in space

Active

Health and wellbeing

Medical devices and diagnostics
This project aims to create a menstrual collection device to be used in reduced-gravity to allow astronauts to transform menstrual-blood (currently seen as waste) as a resource in regenerative life support systems in long term space missions.Two prototypes have been created and tested in parabolic flights. We are now developing a third new design which builds on the lessons of the last iterations. The project started when discussing feminine hygiene management in space with some experts from space agencies. Turns out, not only is menstrual-blood not talked about in a spaceflight context, but it also contains an incredible amount of potential to be re-used, both on Earth and in space! Whilst the main motivation of this project is from a scientific stand-point, it also aims to open a discussion on "taboo" or "dirty" waste and the extent to which we can create value from it....
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Obios (ex Drinkometer)

Active

Medical devices and diagnostics
Obios is redefining obesity treatment with our data-driven prescription system based on the Drinkometer, a medical device, and our software. Targeting the $100B anti-obesity medication market, we enhance prescription precision, moving away from the current trial and error approach. Our Drinkometer tracks ingestive behaviour, the only biomarker directly associated with anti-obesity medications outcome. Our software leverages these insights allowing tailored treatment. This research-based approach enables doctors to make informed prescriptions, improving patient outcomes, cutting healthcare costs and streamlining drug production. With 50 ready-to-buy opinion leaders and strategic pharmaceutical partnerships, Obios is advancing to set a new benchmark in anti-obesity medication prescription....
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TeachAR

Alumni

Education

Medical devices and diagnostics
TeachAR revolutionizes physiotherapy with PoseTeacher, blending Augmented Reality and AI. Engage in fun, supervised exercises, personalized plans, and real-time telepresence. We ensure accurate pose estimation, gamification, and hardware accessibility. Join us in transforming global physiotherapy with innovative technology and personalized care. Empower your recovery journey with TeachAR. Engage in fun, supervised exercises, personalized plans, and real-time telepresence. We ensure accurate pose estimation, gamification, and hardware accessibility. Join us in transforming global physiotherapy with innovative technology and personalized care. Empower your recovery journey with TeachAR....
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